How would the other concepts interrelate with perfusion

How would the other concepts interrelate with perfusion

The key concept with the heart and peripheral vascular system is perfusion.
How would the other concepts interrelate with perfusion? Think of someone with hypertension and heart failure. This will require research of pathophysiology (medical diag, definition, signs & symptoms, treatment/ diagnostic labs ). How is adequate perfusion determined? Post an initial posting, then respond to at least one of your peers