Cell biology questions mostly about GPCR pathway and the MAPK pathway 

Cell biology questions mostly about GPCR pathway and the MAPK pathway

The GPCR pathway begins with ligand binding to the GPCR which causes a
conformational change in the receptor, allowing it to directly bind to the alpha subunit of its g-
protein. This binding results in the loss of GDP and a subsequent binding of GTP and also a
dissociation from the G, bind back with (which varies depending on the specific GPCR and
cell type) and then give up its GTP, bind back with G dimer, and become inactive once again.
There are cases that once the alpha subunit is activated and separated from G dimer, it is the

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